Best Ergonomic Mouse

If you use your mouse all day to work, you may find the straight, ambidextrous design of most mice uncomfortable at the end of a long day at work.

Today there are many mice that are designed with a slanted shape or with a thumb rest to help with ergonomics and create a more comfortable user experience.

While we do not test the long-term effects of ergonomic mice, the following mice are at least somewhat slanted and comfortable in design and have easily accessible buttons.

1. Logitech MX Master 3 – Best Ergonomic Mouse

Best Ergonomic Mouse

The best ergonomic mouse we’ve tested so far if you’re looking for something to use in the office is the Logitech MX Master 3.

This mouse looks very professional with a right-angled design, plus it has a great thumb rest for a very comfortable hand position. It’s great for people who use a palm grip.

This mouse can be used via Bluetooth and with its USB receiver, which makes it quite versatile.

Although it doesn’t perform as well as high-end gaming mice, its main goal is to make the office workflow smoother. It has an unlockable mouse wheel to scroll infinitely through long documents and it even has a second side scroll wheel.

The thumb rest also features a button that can be used to activate gesture commands and you can set different profiles for the different programs and applications you are using.

Unfortunately, it is quite heavy, so you will have to find a sensitivity that does not force you to lift the mouse often, and its wide and large body will not be the best option if you have smaller hands.

On the other hand, this professional mouse makes workflow smoother and is one of the better built and higher quality mice that we have reviewed so far.

Main features :

  • Connectivity : Wireless
  • Type : Standard

Related: Best Razer Mouse

2. Logitech MX Master 2S – Best Ergonomic Mouse For Office Use

Logitech MX Master 2S - Best Ergonomic Mouse For Office Use

If you’re shopping on a budget, take a look at the Logitech MX Master 2S.

Its design and features are very similar to the Logitech MX Master 3, but it is slightly heavier and its side buttons are a bit more difficult to press due to its location.

There are five programmable buttons and it has a slightly higher polling speed, which makes mouse movements a bit smoother.

Still, you get great customization options through its companion software, as well as excellent compatibility with Windows and MacOS, and it can be paired with three devices at the same time to make multitasking a piece of cake.

Overall, the MX Master 3 is slightly better if you can afford it, but the MX Master 2S can perform almost as well and is significantly cheaper.

Main features :

  • Connectivity : Wireless
  • Type : Standard

3. Logitech MX Vertical – Best Vertical Mouse

Logitech MX Vertical - Best Vertical Mouse

The best vertical mouse we’ve tested so far is the Logitech MX Vertical.

Upright mice aim to reduce pronation of the forearm and put the arm in a more natural position.

This should help people who feel a lot of strain on their wrist or forearm after a long day at work.

This mouse is from the professional MX line, like the Logitech MX Master 3 and the Logitech MX Master 2.

It is very well built and its design fits better in the palm of the hand.

Its overall wireless performance is good enough for the office, but it won’t be on a par with gaming mice, which is to be expected.

You can use this mouse via Bluetooth, with its USB receiver, or even by charging it with a cable, which makes it quite versatile.

It is easy to use, although some people may need a little time to get used to its vertical layout.

Also, this very large body will not be very good for people with small hands, as they might have trouble reaching the trackball.

Also, even if it is Bluetooth-enabled, it is a bit difficult to bring it, so it is better to stay at the work desk.

On the other hand, like most of the Logitech mice, it is fully compatible and customizable on MacOS and Windows.

Main features :

  • Connectivity : Wireless
  • Type : Vertical

4. Corsair GLAIVE PRO – Best Ergonomic Mouse For Gaming

Corsair GLAIVE PRO - Best Ergonomic Mouse For Gaming

The best ergonomic gaming mouse we’ve tested is the Corsair GLAIVE PRO.

It should be noted that most gaming mice are not necessarily designed with pure ergonomics in mind, but the sloped design and interchangeable grip options make this the best option if you want something comfortable for long gaming sessions.

Although not the best gaming mouse we’ve tested so far, this wired gaming mouse comes with three different side panels to help you achieve a comfortable fit: one with a thumb rest and two with different grip patterns.

Sensor performance is excellent, and it has a wide adjustable CPI range that can be adjusted in increments of 1, so you can adjust it to your preference.

It has two additional side buttons, an up and down CPI button at the top, and a click of the scroll wheel, all of which can be reprogrammed within Corsair’s excellent iCUE software.

The software is compatible with both Windows and MacOS, which is quite rare for a gaming mouse and allows you to customize all aspects of the mouse.

Unfortunately, like many wired gaming mice, the cable is quite stiff and holds many folds of its packaging.

On the bright side, the mouse is suitable for a wide variety of hand sizes, and everyone should be able to easily reach each button with a claw grip, while only extra-large hands will likely have a difficult time with palm grip.

Overall, if you’re looking for a mouse for extended gaming sessions, the sloped design and interchangeable grip panels make it the most comfortable option.

Main features :

  • Connectivity : Cable
  • Type : Standard

5. Anker Wireless – Best Budget Ergonomic Mouse

Anker Wireless - Best Budget Ergonomic Mouse

The best budget-friendly ergonomic mouse we’ve tested to date is the Anker Wireless Vertical Mouse.

This wireless mouse has a fairly standard upright design and feels surprisingly well-made for its low price.

It is very comfortable to use and its vertical design puts the wrist in a more neutral position.

It is designed to be used with the palm of the hand, although its larger size means that those with small hands may have a difficult time reaching all the buttons comfortably.

Although the click latency is quite high, this mouse is not designed for gaming and you are unlikely to notice any lag in daily use.

Unfortunately, although its IPC is adjustable, even the lowest setting is high, which will cause cursor movement that may be too fast for most people, so you may have to change the speed of the cursor in the operating system settings.

Also, while the mouse has two well-placed thumb buttons, there is no add-on software, so you can’t reprogram them without using third-party software.

Overall, this is a pretty decent ergonomic mouse that has a superior look and feel compared to its low price.

Although we don’t do any tests on the long-term effects of upright mice, they are advertised to be more natural and many people seem to find them more comfortable after using a computer all day at work.

If you’re curious to try a vertical mouse but don’t want to spend a ton, this is a great choice.

Main features :

  • Connectivity : Wireless
  • Type : Vertical

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